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 帕金森症可以治吗？ |
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帕金森症可以治吗？ -- 木辛 - (312 Byte) 2009-7-14 周二, 13:24 (1413 reads) |
黄埔半期
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作者：黄埔半期 在 海归茶馆 发贴, 来自【海归网】 http://www.haiguinet.com
Mayo Clinic 可能有很多即使在美国的人都没有听说过，但是美国排名第一的医院。
权威的说法见下。基本上就是说情况复杂，治疗方法很多，但不是对谁都有效，并且都没有达到能治愈的地步。
https://www.mayoclinic.org/parkinsons-disease/
Overview
According to the National Institute of Neurological Disorders and Stroke, at least 1 million people are believed to suffer from Parkinson's disease, and about 50,000 new cases are reported each year in the United States. These figures are expected to increase as the population ages.
Nearly 4,000 patients with Parkinson's disease are treated each year by neurology and neurosurgery specialists in Mayo Clinic's movement disorders programs. Patients receive state-of-the-art treatment and have opportunities to participate in valuable research studies and clinical trials. Read more about movement disorders.
Diagnosis
No specific test can diagnose Parkinson's disease. Diagnosis is usually made based on the patient's history and a comprehensive neurologic examination. Similar symptoms can be caused by certain medications and by other degenerative brain conditions.
Getting an accurate diagnosis is key to starting appropriate treatment that may help manage symptoms for years. Mayo Clinic has extensive experience in the evaluation, differential diagnosis and treatment of Parkinson's disease.
Treatment Options
Parkinson's disease has no cure. People who are only mildly affected may need no treatment at first. As symptoms progress, various treatment approaches are available. Read more about Parkinson's disease treatment options.
Treatment
People who are only mildly affected by Parkinson's disease may need no treatment at first. As symptoms progress, various treatment approaches are available.
Medication
Medication selection and dosage are tailored to the individual. The doctor considers factors such as severity of symptoms, age and presence of other medical conditions. Every patient responds differently to a medication or dosage level, so this process involves experimentation, persistence, and patience. As the disease progresses, drug dosages may need to be modified. Sometimes drugs are combined. Patients need to receive care from doctors who have extensive experience treating all stages of Parkinson's disease — increasing the effectiveness of treatment at every stage of the disease.
Levodopa, a substance normally found in the body in limited amounts, is usually the first medication prescribed. Taken orally, levodopa can be converted by the body into dopamine the body needs.
Another class of drugs, dopamine agonists, is also useful at reducing symptoms and can be used singly or in conjunction with levodopa. Dopamine agonists were introduced 20 years ago. Agonists are chemical substances capable of combining with part of a cell and initiating a reaction or activity.
In 1998, the first in a new class of Parkinson's disease drugs (COMT inhibitors) was approved by the Food and Drug Administration. The COMT inhibitors prolong effects of levodopa therapy by blocking an enzyme that can break down levodopa.
Surgery
In severely affected patients, surgical treatments such as ablation, deep brain stimulation, and pallidotomy may control some symptoms.
Ablation
This procedure locates, targets, and then ablates (destroys) a clearly defined area of the brain affected by Parkinson's. The object is to destroy tissue that produces abnormal chemical or electrical impulses that produce abnormal movements. This approach is done less frequently, in favor of deep brain stimulation.
Deep Brain Stimulation (DBS)
DBS targets areas in the brain where uncontrolled movements originate. The targeted region is inactivated, not destroyed, by an implanted electrode. The electrode is connected via a wire running beneath the skin to a stimulator and battery pack in the patient's chest.
Mayo Clinic has extensive expertise in determining which patients would benefit from the surgery. Read more about deep brain stimulation.
Palllidotomy
Pallidotomy, (named for the pallidum area of the brain) is a delicate surgical procedure that targets a precise area to control certain symptoms. A fine probe measures abnormal electrical activity. Another probe delivers small electrical shocks. The patient, who is awake during the surgery, describes the effects to pinpoint the area for treatment. The surgeon then burns a tiny hole in the cells. Results are almost immediate.
Cerebral Transplantation
Dopamine-producing cells are implanted into the brain. The cells used for transplantation may come from fetal cells or embryonic stem cells.
At present, this surgery is experimental and much research needs to be done before it can be considered routinely. Mayo Clinic currently does not offer this surgery.
Complementary Treatments
Numerous therapies and nutritional supplements may help relieve symptoms and improve quality of life.
Physical therapy can help strengthen and tone underused muscles, and give rigid muscles a better range of motion. The goal is to help build body strength, improve balance, overcome gait problems and improve speaking and swallowing. Simple physical activities such as walking, gardening and swimming can foster a sense of well-being. For some patients, soothing massage may provide relief from muscle rigidity and may have other neuromuscular benefit(s).
作者：黄埔半期 在 海归茶馆 发贴, 来自【海归网】 http://www.haiguinet.com
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 帕金森症可以治吗？ -- 木辛 - (312 Byte) 2009-7-14 周二, 13:24 (1413 reads) - 权威说 “Parkinson's disease has no cure” -- 黄埔半期 - (5484 Byte) 2009-7-15 周三, 04:08 (416 reads)
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