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 The proliferation of human bird-flu cases －－ and deaths. As a company manager how do you prepare for |
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ceo/cfo
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加入时间: 2004/11/05
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作者：ceo/cfo 在 海归商务 发贴, 来自【海归网】 http://www.haiguinet.com
this???
(zt)－－ shows no sign of slowing, posing new questions for scientists who track the outbreak and some ethical dilemmas for companies preparing for a potential pandemic.
An Indonesian girl has become the latest person to die of bird flu, Indonesian officials tell the BBC. If the local tests are confirmed by the World Health Organization, she will be the 13th person to die of the disease in Indonesia and the 76th in East Asia since the resurgence of H5N1 began there at the end of 2003. In Turkey, a teenage girl has died of suspected bird flu, and if that case is confirmed, her death will be the country's fourth since human infections began there a few weeks ago. The 12-year-old girl had been in contact with sick birds though preliminary tests came back negative for the deadly H5N1 strain, the Associated Press reports. But her younger brother tested positive for H5N1, and authorities suspect the virus indeed caused her death and are conducting further tests. So far 19 people in Turkey have tested positive for H5N1, all after coming into contact with infected birds. Turkey said today that it has slaughtered 764,000 fowl in its fight to contain the outbreak, and the Turkish cabinet was meeting to review the crisis.
Researchers have now sequenced the bird-flu viruses that claimed the first two Turkish victims earlier this month, and say that one of them contains a worrying mutation, Nature reports. This genetic tweak can make the H5N1 virus more adapted to humans than to birds, and more adapted to the nose and throat than to the lungs. And this latter effect could help to increase the chances of bird flu being transmitted between people, researchers say. They add that many more mutations would probably be necessary before the virus is capable of sparking a full-blown pandemic, in which disease spreads quickly from person to person.
Companies around the world are grappling with a host of thorny issues as they prepare plans to keep their businesses operating if employees fall ill during a bird-flu pandemic that could strike tomorrow, in 10 years, or never, The Wall Street Journal says. For example, last year, Procter & Gamble asked its company doctors whether it should try to secure a private stash of the avian-influenza drug Tamiflu for its staff of 25,000 in Asia. And they're still debating the question. "How ethical would it be if we were holding supplies that the general public didn't have access to but badly needed?" asks Shivanand Priolkar, the company's medical leader for southern Asia. He even worries that "people could come to know you have a life-saving medicine and you could make yourself a target." Emotional and ethical issues are coming up as well, especially given the difficulty in obtaining Tamiflu, the Roche Holding antiviral that is the drug of choice against bird flu in humans.
Roche agreed last year to license the drug's manufacture to various partners, and it has been ramping up production. But with Tamiflu still in short supply, managers who socked some away last year are struggling with how to distribute it equitably in the event of a pandemic. Companies that didn't stockpile it are wrestling with the question of whether they even want it －－ or can afford to forgo it. Roche divides its Tamiflu stock into two categories, one for seasonal flu and one for pandemic flu. Months ago, it set aside some of its Tamiflu stocks for seasonal flu use and says there is no shortage of supplies for this purpose. But there is a shortage for pandemic orders, the Journal reports. It is unusual for a company to divide a drug into stockpiles like this, but the level of demand for Tamiflu is also rare. Roche declines to say how much Tamiflu it has shipped for each purpose. Separately, the U.S. Centers for Disease Control and Prevention over the weekend urged doctors to stop prescribing two of four antiviral drugs used to treat seasonal influenza because the dominant strain circulating this winter has rapidly become overwhelmingly resistant to them. One of the two still effective is oseltamivir, or Tamiflu
作者：ceo/cfo 在 海归商务 发贴, 来自【海归网】 http://www.haiguinet.com
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 The proliferation of human bird-flu cases －－ and deaths. As a company manager how do you prepare for -- ceo/cfo - (4095 Byte) 2006-1-17 周二, 02:33 (1099 reads)
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